王雪贞
编辑:js77999金莎官网编辑  来源:js77999金莎官网原创  浏览次数: 发布日期:2013-09-01 16:34:31 【

2004-2009   华中科技大学同济医学院神经病学博士

2009-2012   js77999金莎官网神经内科,   讲师,主治医师

2012-2014   美国德克萨斯大学圣安东尼奥健康科学中心, 博士后

2014-           滨州医学院代谢与神经精神疾病研究所

研究方向:神经退行性疾病机理研究,抗抑郁机理研究

代表论著:

1.D Zhang1, X Wang1,2, B Wang1,3, J C Garza1, X Fang1, J Wang1, P E Scherer4, R Brenner3, W Zhang1 and X-Y Lu1,2,5 Adiponectin regulates contextual fear extinction and intrinsic excitability of dentate gyrus granule neurons through AdipoR2 receptors Molecular Psychiatry advance online publication 3 May 2016; doi: 10.1038/mp.2016.58 

2.Carrier N, Wang X (co-first author), Sun L, Lu XY * (2015) Sex-specific and estrous cycle-dependent antidepressant-like effects and hippocampal Akt signaling of leptin. Endocrinology, in press.

3. Wang X, Zhang D, Lu XY * (2015) Dentate gyrus-CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin. Mol Psychiatry. 20(4):509 -519. 

4.Zhang M, Wang X, Jiang F, Wang W, Vincent I, Bu B. Mitotic epitopes are incorporated into age-dependent neurofibrillary tangles in Niemann-Pick disease type C. Brain Pathol. 2010, 20(2):367-77.(Co-First author).

5.Wang X ,Tang R, Xue Z, Jiang F, Zhang M, Bu B. Lentivector-mediated RNAi efficiently downregulates expression of murine TNF-alpha gene in vitro and in vivo. J Huazhong Univ Sci Technolog Med Sci. 2009, 29(1):112-7. 

6.Xue Z, Wang X, Liu F, Hu S, Zhu S, Zhang S, Bu B. Intracranial hypertension syndrome in Systemic Lupus Erythematosus: clinical analysis and review of the literature. J Huazhong Uni Sci Techol, 2009, 29(1):107-111.(co-first author). 

7.Feng JIANG, Xuezhen WANG, Zheng XUE, Suming ZHANG, Siyu FANG, Min ZHANG. Lentivector-mediated RNAi efficiently downregulates expression of murine cdk4 gene in vitro. Front. Med. 2009,3(3):287-91. 

8.Zhang M, Hallows JL, Wang X, Bu B, Wang W, Vincent I. Mitogen-activated protein kinase activity may not be necessary for the neuropathology  of Niemann-Pick type C mice. J Neurochem. 2008, 107(3):81


承担课题:

1.国家自然科学基金项目:Grb10对AD相关的认知功能障碍和神经病理变化的影响及其机制研究。立项时间:2015-2017年,负责人:王雪贞。

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